Energetically Demanding transport in a Supramolecular Assembly
Chuyang Cheng, Paul R. McGonigal, Wei-Guang Liu, Hao Li, Nicolaas A. Vermeulen, Chenfeng Ke, Marco Frasconi, Charlotte L. Stern, William A. Goddard III, J. Fraser Stoddart
Abstract
A challenge in contemporary chemistry is the realization of artificial molecular machines that can perform work in solution on their environments. Here, we report on the design and production of a supramolecular flashing energy ratchet capable of processing chemical fuel generated by redox changes to drive a ring in one direction relative to a dumbbell toward an energetically uphill state. The kinetics of the reaction pathway juxtapose a low energy [2]pseudorotaxane that forms under equilibrium conditions with a high energy, metastable [2]pseudorotaxane which resides away from equilibrium.
Group Members
Cheng, C., McGonigal, P. R., Liu, W., Li, H., Vermeulen, N. A., Ke, C., Frasconi, M., Stern, C. L., III, W. A. G., & Stoddart, J. F. (2014). Energetically Demanding transport in a Supramolecular Assembly. *J. Am. Chem. Soc.*, *136*(42), 14702-14705. https://doi.org/10.1021/ja508615f