Enhancing 2-Iodoxybenzoic Acid Reactivity by Exploiting a Hypervalent Twist
Julius T. Su, William A. Goddard III
2005J. Am. Chem. Soc., 127(41), 14146-14147103cited
Abstract
A rearrangement of hypervalent bonds, or twisting, proves to be the rate-determining step in the 2-iodoxybenzoic acid (IBX) oxidation of alcohols. From this insight, derived from density functional theory calculations, we explain why IBX oxidizes large alcohols faster than small ones and propose a modification to the reagent predicted to make it more active.
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Cite this publication
Su, J. T. & III, W. A. G. (2005). Enhancing 2-Iodoxybenzoic Acid Reactivity by Exploiting a Hypervalent Twist. *J. Am. Chem. Soc.*, *127*(41), 14146-14147. https://doi.org/10.1021/ja054446x