Mechanism of C−F Reductive Elimination from Palladium(IV) Fluorides
Takeru Furuya, Diego Benítez, Ekaterina Tkatchouk, Alexandra E. Strom, Pingping Tang, William A. Goddard III, Tobias Ritter
Abstract
The first systematic mechanism study of C−F reductive elimination from a transition metal complex is described. C−F bond formation from three different Pd(IV) fluoride complexes was mechanistically evaluated. The experimental data suggest that reductive elimination occurs from cationic Pd(IV) fluoride complexes via a dissociative mechanism. The ancillary pyridyl-sulfonamide ligand plays a crucial role for C−F reductive elimination, likely due to a κ^3 coordination mode, in which an oxygen atom of the sulfonyl group coordinates to Pd. The pyridyl-sulfonamide can support Pd(IV) and has the appropriate geometry and electronic structure to induce reductive elimination.
Group Members
Furuya, T., Benítez, D., Tkatchouk, E., Strom, A. E., Tang, P., III, W. A. G., & Ritter, T. (2010). Mechanism of C−F Reductive Elimination from Palladium(IV) Fluorides. *J. Am. Chem. Soc.*, *132*(11), 3793-3807. https://doi.org/10.1021/ja909371t