Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: C-C Bond Formation through Bimolecular Reductive Elimination
William E., Jr. Brenzovich, Diego Benítez, Aaron D. Lackner, Hunter P. Shunatona, Ekaterina Tkatchouk, William A. Goddard III, F. Dean Toste
2010Angewandte Chemie International Edition in English, 49(32), 5519-5522
Abstract
Gold-ilocks and the 3 mol % catalyst: Bimetallic gold bromides allow the room temperature aminoarylation of unactivated terminal olefins with aryl boronic acids using Selectfluor as an oxidant. A catalytic cycle involving gold(I)/gold(III) and a bimolecular reductive elimination for the key CC bond-forming step is proposed. dppm= bis(diphenylphosphanyl)methane.
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Cite this publication
Brenzovich, W. E. J., Benítez, D., Lackner, A. D., Shunatona, H. P., Tkatchouk, E., III, W. A. G., & Toste, F. D. (2010). Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: C-C Bond Formation through Bimolecular Reductive Elimination. *Angewandte Chemie International Edition in English*, *49*(32), 5519-5522. https://doi.org/10.1002/chin.201050030